Compositions and methods for viral sensitization
US-2024360115-A1 · Oct 31, 2024 · US
US8993565B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993565-B2 |
| Application number | US-201414312124-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 23, 2014 |
| Priority date | Jul 2, 2009 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The invention relates to the novel materials of formula (I), wherein each of the substituents R, R1, R2, R3, R4 and R5 is as defined herein. The materials are useful as inhibitors of AKT(PKB) phosphorylation.
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The invention claimed is: 1. A method of treating cancer capable of being modulated by inhibition of AKT phosphorylation in a patient in need thereof comprising administering to said patient an effective dose of a compound according to formula (I): in which: R1 represents an aryl or heteroaryl radical optionally substituted with one or more substituents, which may be…
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Human Necessities · mapped topic
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