7-azaindole derivatives suitable for treatment of cancers

US8993564B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993564-B2
Application numberUS-201214126857-A
CountryUS
Kind codeB2
Filing dateMay 29, 2012
Priority dateJun 24, 2011
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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Abstract

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Compounds of the formula (I) in which R 1 , R 2 and R 3 have the meanings indicated in Claim 1 , are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed treatment of tumours.

First claim

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The invention claimed is: 1. a compound of the formula I in which R 1 denotes H, A, CH 2 CN, CH 2 CONH 2 , CH 2 CONHA′, CH 2 CONA′ 2 , CH 2 COOH, CH 2 COOA′ or CH 2 COHet 1 , R 2 denotes (CH 2 ) n Ar, COAr, (CH 2 ) n Het, Cyc, Alk or A, R 3 denotes CH 3 or (CH 2 ) n NHCOOA′, R 4 denotes phenyl, Alk denotes unbranched or branched alkenyl having 2-6 C atoms,…

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What does patent US8993564B2 cover?
Compounds of the formula (I) in which R 1 , R 2 and R 3 have the meanings indicated in Claim 1 , are inhibitors of PDK1 and cell proliferation/cell vitality and can be employed treatment of tumours.
Who is the assignee on this patent?
Heinrich Timo, Wucherer-Plietker Margarita, Buchstaller Hans-Peter, and 1 more
What technology area does this patent fall under?
Primary CPC classification C07D471/04. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).