Inhibitors of tyk2
US-2024425484-A1 · Dec 26, 2024 · US
US8993560B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993560-B2 |
| Application number | US-201213414873-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 8, 2012 |
| Priority date | Mar 11, 2011 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (SYK) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory diseases and/or allergic conditions, in cancer therapy, specifically heme malignancies, and autoimmune conditions.
Opening claim text (preview).
The invention claimed is: 1. A compound which is: 7-(2-(methyloxy)-6-{[(4-methyl-2-pyridinyl)methyl]oxyl phenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine; or a salt thereof. 2. The compound or salt according to claim 1 , wherein the salt is a pharmaceutically acceptable salt. 3. The compound or salt according to claim 1 , w…
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