8-hydroxy quinoline derivatives for enhancing telomerase reverse transcriptase (TERT) expression
US-12168019-B1 · Dec 17, 2024 · US
US8993535B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993535-B2 |
| Application number | US-201013393571-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 27, 2010 |
| Priority date | Sep 4, 2009 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The compounds are of the class of pyrimidine analogs useful for treating cancer, for example:
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What is claimed is: 1. A compound or a pharmaceutically acceptable salt thereof, said compound being represented by Formula V: wherein: G is H or halo; X is selected from the group consisting of H, F, OR 2 and alkyl; Y is selected from the group consisting of H, F, OR 2 and alkyl; with the proviso that when X═Y═OR 2 , R 2 cannot be H;…
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