Methods and compositions for cancer treatment
US-2024424094-A1 · Dec 26, 2024 · US
Treatment of sialidase 4 (NEU4) related diseases by inhibition of natural antisense transcript to NEU4
US8993533B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993533-B2 |
| Application number | US-201113879100-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 5, 2011 |
| Priority date | Oct 6, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sialidase 4 (NEU4), in particular, by targeting natural antisense polynucleotides of Sialidase 4 (NEU4). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NEU4.
First claim
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What is claimed is: 1. A method of upregulating a function of and/or the expression of a Sialidase 4 (NEU4) polynucleotide selected from SEQ ID No: 1 in a biological system comprising: contacting said system with at least one antisense oligonucleotide 10 to 30 nucleotides in length wherein said at least one oligonucleotide specifically hybridizes to a natural antisense polynucleotide of the Neu4 polynucleotide and has at least 80% sequence identity to a 10 to 30 nucleotide region o…
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- What does patent US8993533B2 cover?
- The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of Sialidase 4 (NEU4), in particular, by targeting natural antisense polynucleotides of Sialidase 4 (NEU4). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of NEU4.
- Who is the assignee on this patent?
- Collard Joseph, Khorkova Sherman Olga, Curna Inc
- What technology area does this patent fall under?
- Primary CPC classification A61K31/7088. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).