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PKD ligands and polynucleotides encoding PKD ligands
US8993531B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993531-B2 |
| Application number | US-201213348515-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 11, 2012 |
| Priority date | Oct 19, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate protein kinase D (PKD) activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to cellular localization signals, epitope tags and/or reporters. The invention also includes polynucleotides encoding the ligands and polyligands.
First claim
Opening claim text (preview).
What is claimed is: 1. A method of inhibiting PKD activity in a cell, said method comprising: (I) transfecting into a cell a nucleic acid molecule comprising a nucleic acid sequence encoding a polypeptide polyligand, wherein each of the polyligand monomers is an amino acid sequence at least 90% identical to a peptide selected from the group consisting of: a) a peptide comprising amino acid residues corresponding to amino acid residues 381-390 of the amino acid sequence of SEQ…
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Chemistry & Metallurgy · mapped topic
- C07K14/4703Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8993531B2 cover?
- The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate protein kinase D (PKD) activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands and polyligands to cellular localization signals, epitope tags and/or reporters.…
- Who is the assignee on this patent?
- Reed Thomas D, Intrexon Corp
- What technology area does this patent fall under?
- Primary CPC classification C07K14/4703. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).