Method of treatment for neutropenia using stable formulations of recombinant human albumin-human granulocyte colony stimulating factor

US8993519B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993519-B2
Application numberUS-201213660915-A
CountryUS
Kind codeB2
Filing dateOct 25, 2012
Priority dateJan 16, 2009
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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Abstract

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Described herein are compositions and methods for treating, preventing and ameliorating diseases and conditions characterized by a lower than normal white blood cell count, such as leukopenia and neutropenia. The compositions and methods include recombinant human albumin-human granulocyte colony stimulating factor. Pharmaceutical formulations including the recombinant fusion protein, and methods of making such formulations are also described.

First claim

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What is claimed is: 1. A method of treating or preventing neutropenia in a human comprising administering to a human exhibiting neutropenia or at risk of developing neutropenia a pharmaceutical composition comprising recombinant human albumin-human granulocyte colony stimulating factor, and at least one pharmaceutically acceptable carrier, wherein the composition has a pH of between 4 and 6.4, wherein the concentration of recombinant human albumin-human granulocyte colony stimulati…

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What does patent US8993519B2 cover?
Described herein are compositions and methods for treating, preventing and ameliorating diseases and conditions characterized by a lower than normal white blood cell count, such as leukopenia and neutropenia. The compositions and methods include recombinant human albumin-human granulocyte colony stimulating factor. Pharmaceutical formulations including the recombinant fusion protein, and method…
Who is the assignee on this patent?
Teva Pharma
What technology area does this patent fall under?
Primary CPC classification A61K38/38. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).