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Compositions and method for treatment of ischemic neuronal reperfusion injury
US8993512B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993512-B2 |
| Application number | US-201414273343-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 8, 2014 |
| Priority date | May 8, 2013 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-drug and the like.
First claim
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What is claimed is: 1. A method of treatment of neuronal reperfusion injury with ischemic neuropathy, the method comprising: administering an effective amount of at least one of a compound having the formulas I, II or III 2. The method of claim 1 wherein the at least one compound is administered in combination with at least one of Vitamin D, Vitamin E and…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Cross-Sectional Technologies · mapped topic
Human Necessities · mapped topic
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- What does patent US8993512B2 cover?
- A method and composition for the treatment of ischemic neuronal reperfusion injury are provided. The composition can include a compound which is a combination of dantrolene and a residue of FMOC-valine. This composition can be used to provide a faster and higher CNS penetration than heretofore experienced with dantrolene. In another form, dantrolene may be formulated as a pro-drug, a pro-pro-dr…
- Who is the assignee on this patent?
- Univ Howard
- What technology area does this patent fall under?
- Primary CPC classification A61K31/4178. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).