Method for enhancing transport of semiconductor nanocrystals across biological membranes

US8993349B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993349-B2
Application numberUS-90595010-A
CountryUS
Kind codeB2
Filing dateOct 15, 2010
Priority dateOct 6, 2000
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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Abstract

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Semiconductor nanoparticle complexes comprising semiconductor nanoparticles in association with cationic polymers are described. Also described are methods for enhancing the transport of semiconductor nanoparticles across biological membranes to provide encoded cells. The methods are particularly useful in multiplex settings where a plurality of encoded cells are to be assayed. Kits comprising reagents for performing such methods are also provided.

First claim

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What is claimed is: 1. A composition, comprising a micelle dispersed in aqueous solution, wherein the micelle comprises: (a) one or more semiconductor nanoparticles encapsulated with a negatively charged amphiphilic polymer, wherein the amphiphilic polymer is a block copolymer or grafted polymer that comprises at least one hydrophilic segment and at least one hydrophobic segment that encapsulates the one or more semiconductor nanoparticles through hydrophobic interaction, and (b…

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What does patent US8993349B2 cover?
Semiconductor nanoparticle complexes comprising semiconductor nanoparticles in association with cationic polymers are described. Also described are methods for enhancing the transport of semiconductor nanoparticles across biological membranes to provide encoded cells. The methods are particularly useful in multiplex settings where a plurality of encoded cells are to be assayed. Kits comprising …
Who is the assignee on this patent?
Bruchez Marcel P, Daniels R Hugh, Dias Jennifer, and 6 more
What technology area does this patent fall under?
Primary CPC classification G01N33/588. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).