Methods of increasing the expression yield of vitamin K-dependent proteins
US-9212214-B2 · Dec 15, 2015 · US
Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
US8993326B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993326-B2 |
| Application number | US-201314043742-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 1, 2013 |
| Priority date | May 2, 2008 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The invention provides methods and compositions for preparing antibodies and antibody derivatives with reduced core fucosylation.
First claim
Opening claim text (preview).
What is claimed is: 1. A mammalian cell culture medium for the production of antibodies or antibody derivatives having reduced core fucosylation, comprising an effective amount of a fucose analog wherein the fucose analog is selected from the group consisting of one of the following formulae (I) or (II): or a biologically acceptable salt or solvate thereof, wherein:…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C12N5/0037Primary
Chemistry & Metallurgy · mapped topic
- C07H13/04Primary
Chemistry & Metallurgy · mapped topic
- C07K16/00Primary
Chemistry & Metallurgy · mapped topic
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Frequently asked questions
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- What does patent US8993326B2 cover?
- The invention provides methods and compositions for preparing antibodies and antibody derivatives with reduced core fucosylation.
- Who is the assignee on this patent?
- Seattle Genetics Inc
- What technology area does this patent fall under?
- Primary CPC classification C12N5/0037. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).