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US-9222082-B2 · Dec 29, 2015 · US
Mutants of Francisella tularensis and uses thereof
US8993302B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993302-B2 |
| Application number | US-201013266466-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 23, 2010 |
| Priority date | Apr 29, 2009 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to a mutant Francisella tularensis strain comprising an inactivated clpB gene and compositions comprising such mutant. Methods of producing the mutant are also described. The present invention also encompasses a method of conferring immunity against F. tularensis in a host, comprising administering the described mutant F. tularensis strain.
First claim
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The invention claimed is: 1. An attenuated Francisella tularensis mutant strain wherein the caseinolytic peptidase B (c/pB) gene is deleted, wherein the mutant is a variant of the wild-type clinical strain of F. tularensis selected from the group consisting of SCHU S4, FS033, FSC 108 and FSC 200. 2. The mutant F. tularensis strain of claim 1 , wherein the mutant is more attenuated than F. tularensis LVS. 3. The mutant F. tularensis…
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Frequently asked questions
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- What does patent US8993302B2 cover?
- The present invention relates to a mutant Francisella tularensis strain comprising an inactivated clpB gene and compositions comprising such mutant. Methods of producing the mutant are also described. The present invention also encompasses a method of conferring immunity against F. tularensis in a host, comprising administering the described mutant F. tularensis strain.
- Who is the assignee on this patent?
- Conlan Joseph Wayne, Sjostedt Anders, Nat Res Council Canada
- What technology area does this patent fall under?
- Primary CPC classification C12N9/90. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).