Water Treatment Unit Comprising a Plurality of Filtration Devices
US-2024308884-A1 · Sep 19, 2024 · US
US8993294B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993294-B2 |
| Application number | US-201013389251-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 10, 2010 |
| Priority date | Aug 10, 2009 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present methods relate to the isolation and concentration of proteins using cross-flow membrane filtration, and to proteins produced by such methods. A feature of the method is that the protein of interest is retained by a cross-flow membrane under certain conditions that promote retention, while under other condition the protein passes through the membrane.
Opening claim text (preview).
What is claimed is: 1. A method for recovering a protein of interest from a culture solution using cross-flow membrane filtration, comprising: subjecting a culture solution comprising a protein of interest to cross-flow membrane filtration using a first cross-flow membrane under a first set of conditions that cause the protein of interest to be retained as retentate to allow purification, concentration, and/or buffer exchange of the protein of interest; exposing the protein of i…
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