Cross-flow membrane filtration-based process for protein recovery

US8993294B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993294-B2
Application numberUS-201013389251-A
CountryUS
Kind codeB2
Filing dateAug 10, 2010
Priority dateAug 10, 2009
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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Abstract

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The present methods relate to the isolation and concentration of proteins using cross-flow membrane filtration, and to proteins produced by such methods. A feature of the method is that the protein of interest is retained by a cross-flow membrane under certain conditions that promote retention, while under other condition the protein passes through the membrane.

First claim

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What is claimed is: 1. A method for recovering a protein of interest from a culture solution using cross-flow membrane filtration, comprising: subjecting a culture solution comprising a protein of interest to cross-flow membrane filtration using a first cross-flow membrane under a first set of conditions that cause the protein of interest to be retained as retentate to allow purification, concentration, and/or buffer exchange of the protein of interest; exposing the protein of i…

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What does patent US8993294B2 cover?
The present methods relate to the isolation and concentration of proteins using cross-flow membrane filtration, and to proteins produced by such methods. A feature of the method is that the protein of interest is retained by a cross-flow membrane under certain conditions that promote retention, while under other condition the protein passes through the membrane.
Who is the assignee on this patent?
Bodo Michael, Heng Meng H, Danisco Us Inc
What technology area does this patent fall under?
Primary CPC classification B01D61/16. Mapped technology areas include Operations & Transport.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).