Rosuvastatin calcium and process for producing intermediate thereof
US-2024360086-A1 · Oct 31, 2024 · US
US8993280B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993280-B2 |
| Application number | US-66414208-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 12, 2008 |
| Priority date | Jun 12, 2007 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present invention provides a method for producing an alkaloid, for example, reticuline, comprising providing dopamine as a substrate for a series of actions of monoamine oxidase, norcoclaurine-6-O-methyltransferase, coclaurine-N-methyltransferase and 3′-hydroxy-N-methylcoclaurine-4′-O-methyltransferase.
Opening claim text (preview).
The invention claimed is: 1. A method for producing reticuline from dopamine, which comprises the steps of: providing a recombinant host cell expressing monoamine oxidase, norcoclaurine-6-O-methyltransferase, coclaurine-N-methyltransferase and 3′-hydroxy-N-methylcoclaurine-4′-O-methyltransferase, wherein the recombinant host cell is obtained by introducing genes encoding monoamine oxidase, norcoclaurine-6-O-methyltransferase, coclaurine-N-methyltransferase and 3′-hydroxy-N-methylc…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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