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PKA ligands and polynucleotides encoding PKA ligands
US8993263B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993263-B2 |
| Application number | US-83489707-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 7, 2007 |
| Priority date | Aug 7, 2006 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate PKA activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a reporter. The invention also includes polynucleotides encoding the ligands and polyligands.
First claim
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What is claimed is: 1. An isolated polynucleotide comprising a nucleotide sequence encoding a polypeptide polyligand comprising monomeric ligands, said polypeptide polyligand having at least 95% sequence identity to the polypeptide of SEQ ID NO: 1, wherein said polypeptide polyligand inhibits protein kinase A activity. 2. A vector comprising the isolated polynucleotide of claim 1 . 3. The isolated polynucleotide of claim 1 , wherein the pol…
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- What does patent US8993263B2 cover?
- The invention relates to kinase ligands and polyligands. In particular, the invention relates to ligands, homopolyligands, and heteropolyligands that modulate PKA activity. The ligands and polyligands are utilized as research tools or as therapeutics. The invention includes linkage of the ligands, homopolyligands, and heteropolyligands to a cellular localization signal, epitope tag and/or a rep…
- Who is the assignee on this patent?
- D Reed Thomas, Intrexon Corp
- What technology area does this patent fall under?
- Primary CPC classification C12N9/12. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).