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Methods and compositions for diagnosis and prognosis of renal injury and renal failure
US8993250B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993250-B2 |
| Application number | US-200913128392-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 10, 2009 |
| Priority date | Nov 10, 2008 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin-12 subunit beta, Interleukin-16, Interleukin-2, 72 kDa type IV collagenase, Matrix metalloproteinase-9, Midkine, and Serum amyloid P-component as diagnostic and prognostic biomarkers in renal injuries.
First claim
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We claim: 1. A method for evaluating renal status in a subject, comprising: obtaining a urine sample from a subject selected for evaluation based on a determination that the subject is at risk of a future acute renal injury; performing one or more assays configured to detect a kidney injury marker selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth factor, Interferon gamma, Interleukin-12 subunit beta, Interleukin-16, Interle…
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- G01N33/68Primary
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
Physics · mapped topic
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- What does patent US8993250B2 cover?
- The present invention relates to methods and compositions for monitoring, diagnosis, prognosis, and determination of treatment regimens in subjects suffering from or suspected of having a renal injury. In particular, the invention relates to using assays that detect one or more markers selected from the group consisting of Clusterin, Heart-type fatty acid binding protein, Hepatocyte growth fact…
- Who is the assignee on this patent?
- Anderberg Joseph, Gray Jeff, Mcpherson Paul, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification G01N33/68. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).