Assay for vascular calcification

US8993247B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8993247-B2
Application numberUS-201113577978-A
CountryUS
Kind codeB2
Filing dateFeb 11, 2011
Priority dateFeb 12, 2010
Publication dateMar 31, 2015
Grant dateMar 31, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

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An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising obtaining a blood sample from an individual and measuring the level of a vesicular compound in a matrix vesicle present in the blood sample from said individual; wherein an increased level of said compound indicates an individual at risk of developing vascular calcification.

First claim

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The invention claimed is: 1. An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising the steps of: obtaining a blood sample from said individual; isolating vascular smooth muscle cell-derived matrix vesicles from the blood sample using antibodies directed to a vascular smooth muscle cell membrane-associated protein; measuring the level of a vesicular compound associated with the vascular smooth muscle cell-derived ma…

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What does patent US8993247B2 cover?
An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising obtaining a blood sample from an individual and measuring the level of a vesicular compound in a matrix vesicle present in the blood sample from said individual; wherein an increased level of said compound indicates an individual at risk of developing vascular calcification.
Who is the assignee on this patent?
Shanahan Catherine M, Kapustin Alexander N, King S College London
What technology area does this patent fall under?
Primary CPC classification G01N33/6893. Mapped technology areas include Physics.
When was this patent published?
Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).