System and methods for performing saliva-based diagnostic screenings
US-2024420847-A1 · Dec 19, 2024 · US
US8993247B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993247-B2 |
| Application number | US-201113577978-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 11, 2011 |
| Priority date | Feb 12, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising obtaining a blood sample from an individual and measuring the level of a vesicular compound in a matrix vesicle present in the blood sample from said individual; wherein an increased level of said compound indicates an individual at risk of developing vascular calcification.
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The invention claimed is: 1. An assay for identifying an individual having or at risk of developing vascular calcification, said assay comprising the steps of: obtaining a blood sample from said individual; isolating vascular smooth muscle cell-derived matrix vesicles from the blood sample using antibodies directed to a vascular smooth muscle cell membrane-associated protein; measuring the level of a vesicular compound associated with the vascular smooth muscle cell-derived ma…
Physics · mapped topic
Physics · mapped topic
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