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Identification of the causative mutation for leopard complex spotting and congenital stationary night blindness in equines and a method for testing for same
US8993232B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993232-B2 |
| Application number | US-201113373911-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 5, 2011 |
| Priority date | Dec 3, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard complex spotting. The method is based on detection of an insertion in an intron in the horse Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) gene.
First claim
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The invention claimed is: 1. A method of screening for, diagnosing or detecting congenital stationary night blindness (CSNB) or detecting or selecting different coat patterns in a horse comprising: (a) amplifying a sample from a the horse with three primers to identify the presence of an insertion of SEQ ID NO: 1 in the TRPM1 gene after position 108,297,929 of horse chromosome 1 (ECA1), wherein the primers are SEQ ID NOs: 2-4 and (b) identifying the horse as a true solid coat co…
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Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
- C12Q1/6883Primary
Chemistry & Metallurgy · mapped topic
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- What does patent US8993232B2 cover?
- Methods are provided for determining whether or not a horse is genetically normal, is a carrier of, or is affected with or predisposed to Congenital Stationary Night Blindness and/or leopard complex spotting. The method is based on detection of an insertion in an intron in the horse Transient Receptor Potential Cation Channel, Subfamily M, Member 1 (TRPM1) gene.
- Who is the assignee on this patent?
- Bellone Rebecca, Holl Heather Marie, Brooks Samantha Ann, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C12Q1/6883. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).