Compositions and methods for accurately identifying mutations
US-2024409996-A1 · Dec 12, 2024 · US
US8993230B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993230-B2 |
| Application number | US-32871508-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 4, 2008 |
| Priority date | Dec 4, 2008 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present invention provides methods, reagents and apparatus for conducting single molecule sequencing in an asynchronous manner. The subject methods and compositions are particularly useful for high throughput and multiplexed sequencing.
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What is claimed is: 1. A method for sequencing a target nucleic acid molecule, the method comprising: (a) providing a first nucleic acid molecule and a second nucleic acid molecule, the first nucleic acid molecule and the second nucleic acid molecule comprising the same sequence as the target nucleic acid molecule, wherein the first nucleic acid molecule is complexed with a first primer and a first polymerase and the second nucleic acid molecule is complexed with a second primer a…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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