Semi-synthetic mithramycin derivatives with anti-cancer activity
US-9447135-B2 · Sep 20, 2016 · US
US8993028B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8993028-B2 |
| Application number | US-201213553820-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jul 20, 2012 |
| Priority date | Aug 10, 2011 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The invention provides a process of purifying Rubusoside from the Rubus suavissimus S. Lee plant extract. The process is useful for producing high purity Rubusoside with purity greater than 95% (dry basis). High purity rubusoside is useful as in combination with other caloric and non-caloric sweeteners as well as non-caloric sweetener in various food and beverage compositions. The high purity rubusoside is useful as non-caloric sweetener in edible and chewable compositions such as any beverages, confectioneries, bakeries, cookies, chewing gums, and alike.
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I claim: 1. A process for purifying Rubusoside from Rubus suavissimus extract comprising the steps of: a. providing an extract of Rubus suavissimus S. Lee leaves; b. dissolving the extract in a first aqueous alcoholic solution to obtain a first mixture; c. inducing crystallization in the first mixture by temperature gradient treatment; d. filtering the first mixture from (c) to obtain a first precipitate and a first filtrate; e. dissolving the first precipitate in a se…
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
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