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Topical pharmaceutical compositions containing nanodroplets for the treatment psoriasis
US8992994B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992994-B2 |
| Application number | US-201113880519-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 18, 2011 |
| Priority date | Oct 21, 2010 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to stable topical pharmaceutical compositions for the treatment of psoriasis. Disclosed are in particular nonoemulsions comprising nano size droplets of one or more anti-psoriasis agents, e.g. clobetasol and/or salicylic acid. These compositions exhibit greater permeability, and improved bioavailability. The invention also relates to processes for the preparation of such compositions.
First claim
Opening claim text (preview).
We claim: 1. A stable topical pharmaceutical composition comprising: (a) 0.01-0.5% clobetasol or a salt or ester thereof; (b) 4-8% salicylic acid (c) 1-5% lactic acid (d) 1-5% polyoxyethylene (20) sorbitan monooleate (e) 3-7% of alcohol (f) 3-7% of lipids (g) 7-12% of oils (h) 0.05-0.5% of butylated hydroxytoluene (i) 0.5-3% a carbomer (j) one or more pH adjusting agents, and (k) water; wherein the composition comprises a particle size of about 250 nm and a p…
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Operations & Transport · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8992994B2 cover?
- The present invention relates to stable topical pharmaceutical compositions for the treatment of psoriasis. Disclosed are in particular nonoemulsions comprising nano size droplets of one or more anti-psoriasis agents, e.g. clobetasol and/or salicylic acid. These compositions exhibit greater permeability, and improved bioavailability. The invention also relates to processes for the preparation o…
- Who is the assignee on this patent?
- Roy Sunilendu Bhushan, Kothari Jay Shantilal, Sheikh Shafiq, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification A61K9/0014. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).