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Polysaccharide derivatives and dosage forms
US8992987B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992987-B2 |
| Application number | US-201214009435-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 29, 2012 |
| Priority date | Apr 6, 2011 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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Polysaccharide derivatives having a median Equivalent Projected Circle Diameter (EQPC) of less than 140 micrometers and a particle size and shape distribution meeting condition A or B or both are useful for preparing dosage forms, particularly for preparing compressed sustained-release dosage forms: A. non-compacted polysaccharide derivative particles have a flowability of at least 45 g/sec through a vertically inverted cone having a vertex angle of about 40 and an outlet diameter of about 50 mm, or B. i) no more than 40 volume percent of the polysaccharide derivative particles are fine particles having a particle length LEFI of less than 40 micrometers and ii) no more than 40 volume percent of the polysaccharide derivative particles are fibrous particles, and the sum of the fine particles and the fibrous particles does not exceed 50 volume percent.
First claim
Opening claim text (preview).
The invention claimed is: 1. A polysaccharide derivative which is a particulate cellulose ether or cellulose ester having a median Equivalent Projected Circle Diameter (EQPC) of at least 30 micrometers and less than 140 micrometers and a particle size and shape distribution such that no more than 40 volume percent of the polysaccharide derivative particles are fine particles having a particle length LEFI of less than 40 micrometers and ii) no more than 40 volume percent of the pol…
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Classifications
- A61K9/2054Primary
Human Necessities · mapped topic
Cross-Sectional Technologies · mapped topic
- A61K47/36Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8992987B2 cover?
- Polysaccharide derivatives having a median Equivalent Projected Circle Diameter (EQPC) of less than 140 micrometers and a particle size and shape distribution meeting condition A or B or both are useful for preparing dosage forms, particularly for preparing compressed sustained-release dosage forms: A. non-compacted polysaccharide derivative particles have a flowability of at least 45 g/sec thr…
- Who is the assignee on this patent?
- L Hote-Gaston Jennifer, Grasman Nicholas S, Theuerkauf Jorg, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K9/2054. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).