Novel Pyridine Compounds
US-2024316020-A1 · Sep 26, 2024 · US
US8992976B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992976-B2 |
| Application number | US-9759606-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 15, 2006 |
| Priority date | Dec 16, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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A pharmaceutical composition is provided according to the invention which is suited for the production of tablets by direct compression and which contains donepezil hydrochloride of polymorphic form I. The polymorphic form I of donepezil hydrochloride in the directly compressed tablet is also stable during long storage.
Opening claim text (preview).
The invention claimed is: 1. A pharmaceutical composition, suited for the production of comprimates by direct compression, said composition containing 2 to 10% by weight donepezil hydrochloride of polymorphic form I characterized by Raman peaks at 67 cm −1 , 631 cm −1 , 654 cm −1 , 755 cm −1 , 831 cm −1 , 1048 cm −1 , 1281 cm −1 , 1306 cm −1 , 1435 cm −1 , 1684 cm −1 , 2839 cm −1 , 2857 cm −1 , 2984 cm −1 , 3005 cm −1 , and 3067 cm −1 , wherein said composition further contains a f…
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