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Bone matrix compositions and methods
US8992965B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992965-B2 |
| Application number | US-55560806-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 1, 2006 |
| Priority date | Nov 1, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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An osteoinductive composition, corresponding osteoimplants, and methods for making the osteoinductive composition are disclosed. The osteoinductive composition comprises osteoinductive factors, such as may be extracted from demineralized bone, and a carrier. The osteoinductive composition is prepared by providing demineralized bone, extracting osteoinductive factors from the demineralized bone, and adding the extracted osteoinductive factors to a carrier. Further additives such as bioactive agents may be added to the osteoinductive composition. The carrier and osteoinductive factors may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, can induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. Also, in some embodiments, the osteoinductive composition can be used as a delivery device to administer bioactive agents.
First claim
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The invention claimed is: 1. A method for producing an osteogenic growth factor composition comprising: providing bone; demineralizing the bone in an acid solution to produce a demineralized bone material and a mineral recovered acid; extracting osteogenic growth factors from the demineralized bone material; and combining the osteogenic growth factors extracted from the demineralized bone material and the mineral recovered acid to produce the osteogenic growth factor composi…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8992965B2 cover?
- An osteoinductive composition, corresponding osteoimplants, and methods for making the osteoinductive composition are disclosed. The osteoinductive composition comprises osteoinductive factors, such as may be extracted from demineralized bone, and a carrier. The osteoinductive composition is prepared by providing demineralized bone, extracting osteoinductive factors from the demineralized bone,…
- Who is the assignee on this patent?
- Behnam Keyvan, Warsaw Orthopedic Inc
- What technology area does this patent fall under?
- Primary CPC classification C07K14/51. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).