Compositions and methods that inhibit il-23 signaling
US-2024425579-A1 · Dec 26, 2024 · US
US8992916B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992916-B2 |
| Application number | US-201314044314-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 2, 2013 |
| Priority date | Oct 21, 2005 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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The present invention relates to human anti-IL-13 binding molecules, particularly antibodies, and to methods for using anti-IL-13 antibody molecules in diagnosis or treatment of IL-13 related disorders, such as asthma, atopic dermatitis, allergic rhinitis, fibrosis, inflammatory bowel disease and Hodgkin's lymphoma.
Opening claim text (preview).
The invention claimed is: 1. A method for treating atopic dermatitis, comprising administering to a subject in need thereof an effective amount of a composition comprising an antibody, or functional fragment thereof, that binds human interleukin-13, wherein said antibody or a functional fragment thereof comprises H-CDR1, H-CDR2 and H-CDR3 selected from (i)-(ii): (i) SEQ ID NO: 6, SEQ ID NO: 8 and SEQ ID NO: 9, respectively; and (ii) SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 10,…
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