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Therapeutic approaches for treating CMT and related disorders
US8992891B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8992891-B2 |
| Application number | US-74496208-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 28, 2008 |
| Priority date | Nov 30, 2007 |
| Publication date | Mar 31, 2015 |
| Grant date | Mar 31, 2015 |
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Abstract
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The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders. More particularly, the invention relates to combined therapies for treating said disease by affecting PMP22 expression in a subject.
First claim
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The invention claimed is: 1. A method for the treatment of Charcot Marie Tooth 1A (CMT1A) disease in a subject in need thereof, comprising administering to the subject an effective amount of a combination of at least two compounds selected from D-sorbitol, baclofen, pilocarpine, naltrexone, methimazole, mifepristone, and ketoprofen, or salts thereof. 2. The method of claim 1 , wherein the compounds are combined for a grouped or separate administration, simultan…
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Classifications
- A61K47/06Primary
Human Necessities · mapped topic
- A61K9/0095Primary
Human Necessities · mapped topic
Human Necessities · mapped topic
- A61K31/197Primary
Human Necessities · mapped topic
- A61K31/485Primary
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8992891B2 cover?
- The present invention relates to compositions and methods for the treatment of the Charcot-Marie-Tooth disease and related disorders. More particularly, the invention relates to combined therapies for treating said disease by affecting PMP22 expression in a subject.
- Who is the assignee on this patent?
- Cohen Daniel, Chumakov Ilya, Guerassimenko Oxana, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K47/06. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 31 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).