Operating a mass spectrometer utilizing mass spectral database search
US-2024230661-A1 · Jul 11, 2024 · US
System and method for performing tandem mass spectrometry analysis
US8987662B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8987662-B2 |
| Application number | US-46604509-A |
| Country | US |
| Kind code | B2 |
| Filing date | May 14, 2009 |
| Priority date | May 14, 2009 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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Abstract
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A system for performing tandem mass spectrometry (MS/MS) analysis of a sample includes a mass spectrometer and a processor. The mass spectrometer is configured to perform a mass spectrometry (MS) scan of an ionized sample to provide a mass of an observed peak corresponding to a precursor ion. The processor is configured to perform operations including determining whether the mass of the observed peak matches a mass of at least one of multiple expected peptides on a dynamic watch list, where the expected peptides correspond to a protein in the sample, and calculating a score of an accuracy of the determination when the mass of the observed peak is determined to match the mass of at least one of the plurality of expected peptides. The precursor ion is excluded from an MS/MS scan when the accuracy score indicates that the determination is accurate.
First claim
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What is claimed is: 1. A system for performing tandem mass spectrometry (MS/MS) analysis of a sample, the system comprising: a mass spectrometer configured to perform a mass spectrometry (MS) scan of an ionized sample to provide a mass of an observed peak corresponding to a precursor ion; and a processor configured to perform operations comprising: determining whether the mass of the observed peak matches a mass of at least one of a plurality of expected peptides on a dynamic w…
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- H01J49/0036Primary
Electricity · mapped topic
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Frequently asked questions
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- What does patent US8987662B2 cover?
- A system for performing tandem mass spectrometry (MS/MS) analysis of a sample includes a mass spectrometer and a processor. The mass spectrometer is configured to perform a mass spectrometry (MS) scan of an ionized sample to provide a mass of an observed peak corresponding to a precursor ion. The processor is configured to perform operations including determining whether the mass of the observe…
- Who is the assignee on this patent?
- Satulovsky Javier E, Agilent Technologies Inc
- What technology area does this patent fall under?
- Primary CPC classification H01J49/0036. Mapped technology areas include Electricity.
- When was this patent published?
- Publication date Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).