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Trans-2-decenoic acid derivative and pharmaceutical agent containing the same
US8987486B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8987486-B2 |
| Application number | US-201113883205-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 1, 2011 |
| Priority date | Nov 2, 2010 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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Abstract
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An object of the present invention is to provide a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof and to provide a pharmaceutical agent which contains said compound as an active ingredient and has a highly safe neurotrophic factor-like activity or an alleviating action for side effect induced by administration of anti-cancer agents. The trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof which is the compound of the present invention is specifically represented by the formula (1): (In the formula, Y is —O—, —NR— or —S—, R is hydrogen atom, alkyl group, dialkylaminoalkyl group or the like and W is a substituent such as dialkylaminoalkyl group) and has a quite high usefulness as a pharmaceutical agent such as a preventive or therapeutic agent for dementia, Alzheimer's disease, Parkinson's disease, depression, etc., a treating or repairing agent for spinal cord injury.
First claim
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The invention claimed is: 1. A trans-2-decenoic acid derivative represented by the following formula (1′) or a pharmaceutically acceptable salt thereof; wherein Y′ is —O—, —NR′— or —S—; W′ is W1′ when Y′ is —O—, W2′ when Y′ is —NR′— or W3′ when Y′ is —S—; R′ is dialkylaminoalkyl group, alkyl group, or hydrogen atom: (1) W1′ is dialkylaminoalkyl group, alkylt…
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- What does patent US8987486B2 cover?
- An object of the present invention is to provide a novel trans-2-decenoic acid derivative or a pharmaceutically acceptable salt thereof and to provide a pharmaceutical agent which contains said compound as an active ingredient and has a highly safe neurotrophic factor-like activity or an alleviating action for side effect induced by administration of anti-cancer agents. The trans-2-decenoic aci…
- Who is the assignee on this patent?
- Iinuma Munekazu, Furukawa Shoei, Naiki Mitsuru, and 4 more
- What technology area does this patent fall under?
- Primary CPC classification C07C327/30. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).