Heterocyclic modulators of lipid synthesis
US-2024400552-A1 · Dec 5, 2024 · US
US8987441B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8987441-B2 |
| Application number | US-201113824723-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 21, 2011 |
| Priority date | Sep 24, 2010 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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The present invention provides a compound having antiviral effects, particularly having growth inhibitory activity on influenza viruses, a preferred example of the compound being a substituted 3-hydroxy-4-pyridone derivative prodrug having cap-dependent endonuclease inhibitory activity.
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The invention claimed is: 1. A compound represented by formula (I): a pharmaceutically acceptable salt, or a solvate thereof: wherein: —C(═O)—P R0 , a) —C(═O)—P R1 , b) —C(═O)-L-P R1 , c) —C(═O)-L-O—P R1 , d) —C(═O)-L-O-L-O—P R1 , e) —C(═O)-L-O—C(═O)—P R1 , f) —C(═O)—O—P R2 , g) —C(═O)—N(P R2 ) 2 , h) —C(═O)—O-L-O…
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