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Substituted pyrimido[1,2-b]indazoles and their use as modulators of the Pi3K/Akt pathway
US8987286B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8987286-B2 |
| Application number | US-201113994517-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 13, 2011 |
| Priority date | Dec 16, 2010 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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Abstract
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Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.
First claim
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The invention claimed is: 1. A compound of formula (I) wherein R1 hydrogen, halogen, cyano, hydroxy, COO(1-6C-alkyl), COOH, 1-6Calkyl, which is optionally substituted with hydroxy, (2-6Calkenyl) which is optionally substituted with COO(1-6Calkyl) or (CO)NR7R8, aryl, whereby the aryl ring is optionally substituted one or two times independently by a group selected…
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Human Necessities · mapped topic
- C07D487/04Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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- What does patent US8987286B2 cover?
- Compounds of Formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals. The compounds of formula (I) a: useful for the treatment of cancer.
- Who is the assignee on this patent?
- Rehwinkel Hartmut, Hägebarth Andrea, Politz Oliver, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C07D487/04. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).