Herpesvirus of turkeys vectored vaccine against avian influenza in poultry

US8986987B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8986987-B2
Application numberUS-201113879822-A
CountryUS
Kind codeB2
Filing dateOct 17, 2011
Priority dateOct 18, 2010
Publication dateMar 24, 2015
Grant dateMar 24, 2015

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Abstract

Official abstract text for this publication.

The present application applies to the field of veterinary vaccines, in particular of vaccines for poultry against avian influenza. The vaccine is based on a recombinant viral vector expressing the haemagglutinin protein of an influenza virus, wherein the vector is herpes virus of turkeys (HVT) and the haemagglutinin gene is driven by a glycoprotein B gene promoter from a mammalian herpesvirus. A vaccine comprising this HVT+HA vector can be used to induce a protective immune response against avian influenza in poultry, and to reduce the spread of AIV. The invention also relates to methods, uses, and vaccines involving the HVT+HA vector.

First claim

Opening claim text (preview).

The invention claimed is: 1. A recombinant herpes virus of turkeys (HVT) vector comprising a heterologous nucleic acid, wherein said heterologous nucleic acid comprises an extended mammalian herpesvirus glycoprotein B (gB) gene promoter operably linked to a nucleotide sequence which encodes an influenza virus (IV) hemagglutinin (HA) protein, wherein the extended mammalian herpesvirus gB gene promoter comprises the nucleotide sequence as in SEQ ID NO: 2. 2. The r…

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What does patent US8986987B2 cover?
The present application applies to the field of veterinary vaccines, in particular of vaccines for poultry against avian influenza. The vaccine is based on a recombinant viral vector expressing the haemagglutinin protein of an influenza virus, wherein the vector is herpes virus of turkeys (HVT) and the haemagglutinin gene is driven by a glycoprotein B gene promoter from a mammalian herpesvirus.…
Who is the assignee on this patent?
Sondermeijer Paulus Jacobus Antonius, Verstegen Iwan, Intervet Inc
What technology area does this patent fall under?
Primary CPC classification A61K39/145. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 24 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).