Ultrasound system for shearing cellular material
US-12066362-B2 · Aug 20, 2024 · US
US8986986B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8986986-B2 |
| Application number | US-201113284364-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 28, 2011 |
| Priority date | Oct 29, 2010 |
| Publication date | Mar 24, 2015 |
| Grant date | Mar 24, 2015 |
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A method of lysing at least one of a cell and a virus, the method including: contacting a sample, which includes at least one of a cell and a virus, with a plurality of beads which are disposed in a first chamber to obtain a combination of the sample and the beads; and agitating the combination of the sample and the beads to lyse the at least one of the cell and the virus, wherein in the first chamber a liquid volume fraction is 0.6 or less, and wherein the liquid volume fraction is a value obtained by dividing a liquid volume of the first chamber by a pure void volume equivalent to a sum of the liquid volume of the first chamber and a void volume of the first chamber.
Opening claim text (preview).
What is claimed is: 1. A method of lysing at least one of a cell and a virus, the method comprising: contacting a sample, which comprises at least one of a cell and a virus, with a plurality of beads which are disposed in a first chamber to obtain a combination of the sample and the beads; and agitating the combination of the sample and the beads to lyse the at least one of the cell and the virus, wherein, in the first chamber, a liquid volume fraction is 0.6 or less, and wh…
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