Process for the Preparation of N-Monosubstituted beta-Amino Alcohols
US-2015361064-A1 · Dec 17, 2015 · US
CXCR2 inhibitors
US8980938B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980938-B2 |
| Application number | US-33798008-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 18, 2008 |
| Priority date | Jun 30, 2006 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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Abstract
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The invention relates to compounds of the formula I in which R1, R2, A, B, X and Y have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and prodrugs thereof are suitable for the prevention and treatment of chemokine mediated diseases.
First claim
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The invention claimed is: 1. A compound of formula I: wherein: X is —CR3=CR4-, —NR7-,or —S—; wherein R3 and R4 are, independently of one another, hydrogen, F, Cl, Br, I, alkyl having 1, 2, 3, 4, 5 or 6 carbon atoms, in which 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 or 13 hydrogen atoms may be substituted by fluorine atoms, cycloalkyl having 1, 2, 3, 4, 5 or 6 c…
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- What does patent US8980938B2 cover?
- The invention relates to compounds of the formula I in which R1, R2, A, B, X and Y have the meanings indicated in the claims, and/or a pharmaceutically acceptable salt and/or a prodrug thereof. Because of their properties as inhibitors of chemokine receptors, especially as CXCR2 inhibitors, the compounds of the formula I and the pharmaceutically acceptable salts and p…
- Who is the assignee on this patent?
- Hachtel Stephanie, Dedio Juergen, Pernerstorfer Josef, and 3 more
- What technology area does this patent fall under?
- Primary CPC classification C07D333/16. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).