Camptothecin analogues, conjugates and methods of use
US-2024269309-A1 · Aug 15, 2024 · US
HDAC inhibiting derivatives of camptothecin
US8980909B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980909-B2 |
| Application number | US-201213977413-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 6, 2012 |
| Priority date | Jan 12, 2011 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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Abstract
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The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R 1 , R 2 , and R 3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound of Formula I, or a pharmaceutically acceptable salt thereof: wherein Z is deleted, C(R a R b ), (CH 2 ) p , (CH 2 ) p NH(CH 2 ) q , CH═N, O, S, C(O), N(R a ), SO 2 , OC(O), C(O)O, OSO 2 , S(O 2 )O, C(O)S, SC(O), C(O)C(O), C(O)N(R a ), N(R a )C(O), S(O 2 )N(R a ), N(R a )S(O 2 ), OC(O)O, OC(O)S, OC(O)N(R a ), OC(O)NH(CH 2 ) p+1 NH(CH 2 ) q , N(…
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Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
- C07D491/22Primary
Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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Frequently asked questions
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- What does patent US8980909B2 cover?
- The disclosure includes hydroxamic compounds of Formula I: (Formula I) wherein Z, L, R 1 , R 2 , and R 3 are defined herein. Also disclosed is a method for treating a neoplastic disease or an immune disease with these compounds.
- Who is the assignee on this patent?
- Chen Yi, Chen Yu, Crystal Biopharmaceutical Llc
- What technology area does this patent fall under?
- Primary CPC classification C07D491/22. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).