Pyridonemorphinan analogs and biological activity on opioid receptors

US8980906B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8980906-B2
Application numberUS-201314105733-A
CountryUS
Kind codeB2
Filing dateDec 13, 2013
Priority dateDec 14, 2012
Publication dateMar 17, 2015
Grant dateMar 17, 2015

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  2. Abstract

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  5. First independent claim

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Abstract

Official abstract text for this publication.

The application is directed to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein , R 1a —R 3a , R 4 , Y and Z a are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic intermediates. Certain compounds of the present invention are especially useful for treating pain.

First claim

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What is claimed is: 1. A compound of Formula I: or a pharmaceutically acceptable salt or solvate thereof, wherein: R 1 is hydrogen, OH, halo, cyano, carboxy, or aminocarbonyl; or alkyl, alkenyl, alkynyl, alkoxy alkenyloxy or alkynyloxy, any of which is optionally substituted with 1, 2, or 3 substituents, each independently selected from the group consisting of hydroxy, halo,…

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What does patent US8980906B2 cover?
The application is directed to compounds of Formula I-A and pharmaceutically acceptable salts and solvates thereof, wherein , R 1a —R 3a , R 4 , Y and Z a are defined as set forth in the specification. The invention is also directed to use of compounds of Formula I-A to treat disorders responsive to the modulation of one or more opioid receptors, or as synthetic int…
Who is the assignee on this patent?
Purdue Pharma Lp
What technology area does this patent fall under?
Primary CPC classification C07D471/22. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).