Fused pyridine, pyrimidine and triazine compounds as cell cycle inhibitors

US8980903B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8980903-B2
Application numberUS-201414453842-A
CountryUS
Kind codeB2
Filing dateAug 7, 2014
Priority dateDec 19, 2007
Publication dateMar 17, 2015
Grant dateMar 17, 2015

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  5. First independent claim

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Abstract

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Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives.

First claim

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We claim: 1. A compound of Formula I enantiomers, diastereomers, and salts thereof wherein W is CH; X is N; A 1 and A 2 together with ring carbon atoms to which they are attached combine to form benzene, cyclopentadiene, pyridine, pyridone, pyrimidine, pyrazine, pyridazine, 2H-pyran, pyrrole, imidazole, pyrazole, triazole, furan, oxazole, isoxazo…

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What does patent US8980903B2 cover?
Compounds, pharmaceutical compositions and methods are provided that are useful in the treatment of CDK4-mediated disorders, such as cancer. The subject compounds are fused pyridine, pyrimide and triazine derivatives.
Who is the assignee on this patent?
Amgen Inc
What technology area does this patent fall under?
Primary CPC classification C07D471/14. Mapped technology areas include Chemistry & Metallurgy.
When was this patent published?
Publication date Tue Mar 17 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).