Unsaturated Hydroxamic Acid Derivatives and Their Use for the Treatment and Prevention of an Ammonia-Associated Disease or Disorder
US-2024293344-A1 · Sep 5, 2024 · US
US8980840B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980840-B2 |
| Application number | US-201013144203-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jan 13, 2010 |
| Priority date | Jan 13, 2009 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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The present invention relates to the management of vaginal health. In particular, the present invention relates to pharmaceutical compositions, and methods of use thereof, for treating diseases associated with compromised boundary lubrication at the vaginal epithelium.
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What is claimed is: 1. A method of treating decreased vaginal boundary lubrication or a disease or condition associated therewith or of improving vaginal boundary lubrication, the method comprising topically administering to a vaginal surface of a subject in need thereof a therapeutically effective amount of isolated or purified lubricin or a lubricating fragment, multimer, or homolog thereof sufficient to improve vaginal boundary lubrication. 2. The method of…
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