Engineered imine reductases and methods for the reductive animation of ketone and amine compounds
US-9193957-B2 · Nov 24, 2015 · US
US8980588B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980588-B2 |
| Application number | US-201013518125-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 21, 2010 |
| Priority date | Dec 25, 2009 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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A method for producing acrylamide from acrylonitrile by a biocatalyst method, wherein both evaporation of acrylonitrile into a gas phase and damaging of a catalyst by stirring are prevented, is provided. In the present invention, the production of acrylamide from acrylonitrile by the biocatalyst method comprises feeding acrylonitrile into an aqueous medium comprising a microbial catalyst.
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What is claimed is: 1. A method for producing acrylamide in an aqueous medium by feeding acrylonitrile to said aqueous medium supplemented with a microbial catalyst(s) while stirring said aqueous medium, comprising: placing, in said aqueous medium, a feed opening of an acrylonitrile feed tube that feeds acrylonitrile to said aqueous medium to prevent an evaporation of acrylonitrile into gas phase and to enhance a reaction yield of acrylamide from acrylonitrile, wherein the feed op…
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