Solid pharmaceutical tablet
US-2024226038-A9 · Jul 11, 2024 · US
US8980291B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980291-B2 |
| Application number | US-98238610-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 30, 2010 |
| Priority date | Oct 29, 1999 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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A solid oral controlled-release oral dosage form of hydrocodone is disclosed. The dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof, and a sufficient amount of a controlled release material to render the dosage form suitable for twice-a-day administration to a human patient, the dosage form providing a C 12 /C max ratio of 0.55 to 0.85, said dosage form providing a therapeutic effect for at least about 12 hours.
Opening claim text (preview).
We claim: 1. A solid oral twice-a-day controlled-release dosage form, wherein the dosage form is a tablet consisting of (i) a plurality of individually coated multiparticulates consisting of matrices individually coated with a coating consisting of ethylcellulose and a wax, the matrices collectively consisting of from about 5 mg to about 60 mg hydrocodone or an equivalent amount of a pharmaceutically acceptable salt thereof, hydroxypropylmethyl cellulose and ethylcellulose, (i…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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