Gene therapy for tuberous sclerosis
US-2024343768-A1 · Oct 17, 2024 · US
US8980261B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8980261-B2 |
| Application number | US-201213984760-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 10, 2012 |
| Priority date | Feb 11, 2011 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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This invention concerns pathological angiogenesis and cancer, related treatment methods, and related compositions. Also disclosed are related diagnosis kits and methods.
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What is claimed is: 1. An antibody, or antigen-binding portion thereof, that binds to IGFBP2, said antibody comprising a heavy chain variable region comprising the amino acid sequence of SEQ ID NO: 9 and a light chain variable region comprising the amino acid sequence of SEQ ID NO: 10. 2. The antibody, or antigen-binding portion thereof, of claim 1 , wherein the antibody is a monoclonal antibody. 3. A monoclonal antibody, or antigen-binding…
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