Compositions and methods for targeted delivery to cells
US-2024390271-A1 · Nov 28, 2024 · US
US8979797B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8979797-B2 |
| Application number | US-201113328674-A |
| Country | US |
| Kind code | B2 |
| Filing date | Dec 16, 2011 |
| Priority date | Dec 16, 2010 |
| Publication date | Mar 17, 2015 |
| Grant date | Mar 17, 2015 |
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Official abstract text for this publication.
The invention relates generally to methods and systems for the treatment of pelvic tissues using a high pressure injection device to deliver a therapeutic composition that includes a large molecule therapeutic agent, such as a nucleic acid or a polypeptide, to a target tissue in the pelvic area. Methods of the invention can improve delivery of the therapeutic agent into the tissue, which can be beneficial for the treatment of a pelvic tissue disorder, such as bladder and prostate tumors.
Opening claim text (preview).
What is claimed is: 1. A method for treating or preventing a disease of the pelvic floor in a subject comprising a step of delivering a composition comprising a therapeutic agent selected from the group consisting of nucleic acids and polypeptides to a tissue of the male or female urogenital tract or lower gastrointestinal tract within the subject's body, wherein the tissue is selected from bladder, prostrate, urethral, kidney, vaginal, and endometrial tissues, and wherein the nucl…
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
Human Necessities · mapped topic
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