Systems and methods for nerve imaging

US8977331B2 · US · B2

Patent metadata
FieldValue
Publication numberUS-8977331-B2
Application numberUS-201213713745-A
CountryUS
Kind codeB2
Filing dateDec 13, 2012
Priority dateDec 13, 2012
Publication dateMar 10, 2015
Grant dateMar 10, 2015

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Abstract

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Systems and methods for imaging are presented. The method includes producing excitation light configured to induce fluorescence in an imaging agent that selectively binds to a target species in a region of interest (ROI) of a subject that also includes a background species. A first and a second spectral region are selected such that a determined difference between fluorescence corresponding to the target and the background species in the first spectral region differs from a corresponding difference in the second spectral region. First and second fluorescence images are generated from the fluorescence corresponding to the first and second spectral regions. Additionally, a fluorescence ratio for the background species in the first and second fluorescence image is determined. The first fluorescence image is then multiplied or divided with the determined ratio to generate an intermediate image that is subtracted from the second fluorescent image to reconstruct a background-subtracted image.

First claim

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The invention claimed is: 1. An imaging system, comprising: one or more illumination sources configured to produce excitation light that induces fluorescence emissions in an imaging agent configured to bind to a target species in a region of interest of a subject, wherein the region of interest comprises the target species and a background species; at least one optical element configured to separate the fluorescence emissions into a first spectral region and a second spectral re…

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What does patent US8977331B2 cover?
Systems and methods for imaging are presented. The method includes producing excitation light configured to induce fluorescence in an imaging agent that selectively binds to a target species in a region of interest (ROI) of a subject that also includes a background species. A first and a second spectral region are selected such that a determined difference between fluorescence corresponding to …
Who is the assignee on this patent?
Gen Electric
What technology area does this patent fall under?
Primary CPC classification A61B1/000094. Mapped technology areas include Human Necessities.
When was this patent published?
Publication date Tue Mar 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
What related patents are in patentsdb?
We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).