Traditional Chinese medicine composition for treating dermatophytosis and bromhidrosis and application thereof
US-12090184-B2 · Sep 17, 2024 · US
US8975296B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8975296-B2 |
| Application number | US-201313847794-A |
| Country | US |
| Kind code | B2 |
| Filing date | Mar 20, 2013 |
| Priority date | May 14, 2008 |
| Publication date | Mar 10, 2015 |
| Grant date | Mar 10, 2015 |
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The instant invention relates to pharmaceutical compositions containing cathespin K inhibitors. Also disclosed are processes for making said pharmaceutical compositions.
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What is claimed is: 1. A pharmaceutical composition comprising from 1% to 95% by weight of an amorphous cathepsin K inhibitor system and from 5% to 99% by weight of excipients comprising a diluent, a glidant, a lubricant, a surfactant and a disintegrant, wherein the amorphous cathepsin K inhibitor system comprises a cathepsin K inhibitor, which is N 1 -(1-cyanocyclopropyl)-4-fluoro-N 2 -{(1S)-2,2,2-trifluoro-1-[4′-(methylsulfonyl)-1,1′-biphenyl-4-yl]ethyl}-L-leucinamide, and a poly…
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