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Ether benzotriazole derivatives
US8975286B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8975286-B2 |
| Application number | US-201013391315-A |
| Country | US |
| Kind code | B2 |
| Filing date | Aug 16, 2010 |
| Priority date | Aug 20, 2009 |
| Publication date | Mar 10, 2015 |
| Grant date | Mar 10, 2015 |
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Abstract
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The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
First claim
Opening claim text (preview).
What is claimed is: 1. A compound according to Formula A or a pharmaceutically acceptable salt thereof, wherein: W is Cl, Br, CN or CF 3 ; R 1 is selected from the group consisting of: C 1-8 alkyl, C 2-8 alkenyl, C 2-8 alkynyl, C 3-6 cycloalkyl and C 3-6 cycloalkylC 1-4 alkyl, any of which may bear up to 5 halogen substituents; each R 2 is independently selected fr…
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Human Necessities · mapped topic
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8975286B2 cover?
- The present invention is directed to ether benzotriazole derivatives which are potentiators of metabotropic glutamate receptors, particularly the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to…
- Who is the assignee on this patent?
- Dudkin Vadim Y, Fraley Mark E, Wang Cheng, and 5 more
- What technology area does this patent fall under?
- Primary CPC classification C07D417/14. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 10 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).