Methods for Nucleic Acid Cleavage
US-2024417778-A1 · Dec 19, 2024 · US
US8975017B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8975017-B2 |
| Application number | US-73493408-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 3, 2008 |
| Priority date | Dec 3, 2007 |
| Publication date | Mar 10, 2015 |
| Grant date | Mar 10, 2015 |
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Official abstract text for this publication.
A process concentrates nucleic acid molecules to be detected of a sample on a surface, with capture molecules that specifically bind the nucleic acid molecules. A support material has a capture probe that can specifically be linked to the nucleic acid molecules to be detected to give complexes. The support material and the nucleic acid molecules of the sample are incubated to form the complexes. The complexes are moved to the surface. At least one portion of the complexes becomes bound to the capture molecules via the capture probe.
Opening claim text (preview).
The invention claimed is: 1. A process for concentrating nucleic acid molecules on a surface of a sensor field of a biochip of a sample, for detection of the nucleic acid molecules, comprising the following steps: (a) providing magnetic beads with transfer molecules immobilized thereon, which are configured to hybridize to a first portion of the nucleic acid molecules thereby forming complexes that comprise the magnetic beads, the transfer molecules, and the nucleic acid molecules…
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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