Methods for treatment of cancer with an anti-tigit antagonist antibody
US-2024424092-A1 · Dec 26, 2024 · US
US8974794B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8974794-B2 |
| Application number | US-201414254453-A |
| Country | US |
| Kind code | B2 |
| Filing date | Apr 16, 2014 |
| Priority date | Feb 25, 2009 |
| Publication date | Mar 10, 2015 |
| Grant date | Mar 10, 2015 |
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The invention pertains to methods of using CεmX peptides (e.g., GLAGGSAQSQRAPDRVL; SEQ ID NO:2) that can bind effectively induce immune responses to membrane-bound IgE (mIgE) expressed on the surface of human B lymphocytes.
Opening claim text (preview).
What is claimed: 1. A method of inducing an immune response, comprising: administering to a human subject in need thereof an effective amount of an immunogen selected from the group consisting of GLAGGSAQSQRAPDRVL (SEQ ID NO:2) and HSGQQQGLPRAAGGSVPHPR (SEQ ID NO:3); and an adjuvant. 2. The method of claim 1 , wherein the immunogen is GLAGGSAQSQRAPDRVL (SEQ ID NO:2). 3. The method of claim 1 , wherein the immunogen is HSGQQQGLPRAAGGSVPHP…
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