Method of measuring blood component, sensor used in the method, and measuring device
US-9213012-B2 · Dec 15, 2015 · US
US8972196B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8972196-B2 |
| Application number | US-79446610-A |
| Country | US |
| Kind code | B2 |
| Filing date | Jun 4, 2010 |
| Priority date | Feb 6, 2007 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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Disclosed are embodiments that relate to algorithms and methods for calibrating an analyte sensor, and more particularly, to algorithms for calibrating an optical glucose sensor comprising an equilibrium fluorescent chemical indicator system. In particular, a method of detecting an analyte concentration is disclosed where a modified Michaelis-Menten equation comprising Michaelis-Menten parameters is used to characterize the signal generated by the analyte sensor.
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What is claimed is: 1. A method for determining glucose concentration in a physiologic fluid, the method comprising: providing an optical sensor comprising a non-enzymatic, equilibrium fluorescence chemical indicator system disposed along a distal region of an optical fiber, the chemical indicator system comprising a fluorophore operably coupled to a glucose binding moiety, wherein the fluorophore is configured to generate a fluorescent emission signal upon excitation with light,…
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