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Purification method
US8969580B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8969580-B2 |
| Application number | US-201013517276-A |
| Country | US |
| Kind code | B2 |
| Filing date | Oct 8, 2010 |
| Priority date | Oct 8, 2009 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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Abstract
Official abstract text for this publication.
A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol (18F) Injection for the imaging of b amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [18F]flutemetamol by means of solid phase extraction (SPE).
First claim
Opening claim text (preview).
The invention claimed is: 1. A purification process comprising the following steps: (a) passing a diluted crude product reaction mixture comprising [18F]flutemetamol through a first reverse phase solid phase extraction (SPE) cartridge; (b) washing said first reverse phase SPE cartridge with a water/acetonitrile, tetrahydrofuran(THF)/water, methanol(MeOH)/water or isopropanol/water mixture; (c) rinsing said first reverse phase SPE cartridge with water once step (b) is completed…
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Classifications
- A61K51/0402Primary
Human Necessities · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
- C07D277/66Primary
Chemistry & Metallurgy · mapped topic
Operations & Transport · mapped topic
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Frequently asked questions
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- What does patent US8969580B2 cover?
- A diagnostic imaging agent useful for positron emission tomography (PET) imaging as well as to improved hardware for producing such imaging agents is described. Flutemetamol (18F) Injection for the imaging of b amyloid plaques in the brain and methods and devices for preparing same are described including the automated synthesis and purification of [18F]flutemetamol by means of solid phase extr…
- Who is the assignee on this patent?
- Horn Eric, Fairway Steven, Mantzilas Dimitrios, and 2 more
- What technology area does this patent fall under?
- Primary CPC classification A61K51/0402. Mapped technology areas include Human Necessities.
- When was this patent published?
- Publication date Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).