Antimicrobial agents
US-9475783-B2 · Oct 25, 2016 · US
Inhibitors of STAT3
US8969578B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8969578-B2 |
| Application number | US-200913119575-A |
| Country | US |
| Kind code | B2 |
| Filing date | Sep 17, 2009 |
| Priority date | Sep 17, 2008 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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Abstract
Official abstract text for this publication.
Disclosed herein are compounds derived from a chemical structure according to the formula (I) wherein X comprises oxygen or sulfur, R 1 comprises a phenyl or naphthyl group, R 2 comprises an amide group and R 3 comprises a phosphate group. The disclosed compounds demonstrate inhibitory activity against STAT3, a protein found in certain tumor tissues and which promotes cellular overproliferation and resistance to apoptosis. The invention includes compositions containing the disclosed compounds, as well as methods of treatment therewith.
First claim
Opening claim text (preview).
That which is claimed: 1. A compound having a chemical structure according to the formula: wherein X is oxygen or sulfur, R 1 is a phenyl group or a naphthyl group, and R 2 is an amide group, wherein the compound is not: 2. A pharmaceut…
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Chemistry & Metallurgy · mapped topic
Human Necessities · mapped topic
- C07D263/34Primary
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
Chemistry & Metallurgy · mapped topic
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- What does patent US8969578B2 cover?
- Disclosed herein are compounds derived from a chemical structure according to the formula (I) wherein X comprises oxygen or sulfur, R 1 comprises a phenyl or naphthyl group, R 2 comprises an amide group and R 3 comprises a phosphate group. The disclosed compounds demonstrate inhibitory activity against STAT3, a protein found in certain tumor tissues and which promotes cellular overproliferat…
- Who is the assignee on this patent?
- Turkson James, Hamilton Andrew D, Univ Central Florida Res Found
- What technology area does this patent fall under?
- Primary CPC classification C07D263/34. Mapped technology areas include Chemistry & Metallurgy.
- When was this patent published?
- Publication date Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).