β-glucuronidase inhibitor
US-9200269-B2 · Dec 1, 2015 · US
US8969564B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8969564-B2 |
| Application number | US-201414188141-A |
| Country | US |
| Kind code | B2 |
| Filing date | Feb 24, 2014 |
| Priority date | Mar 9, 2012 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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The present disclosure is generally directed to compounds which can inhibit AAK1 (adaptor associated kinase 1), compositions comprising such compounds, and methods for inhibiting AAK1.
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What is claimed is: 1. A method of inhibiting adaptor associated kinase 1 (AAK1) activity, comprising contacting AAK1 with a compound of formula (I), or a pharmaceutically acceptable salt thereof, wherein: R 1 and R 2 are independently selected from hydrogen, C 3 -C 6 cycloalkyl, and C 1 -C 3 alkyl wherein the C 1 -C 3 alkyl is optionally substituted with one, two, or…
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