Method for immunosensing on a lipid layer
US-2024133878-A1 · Apr 25, 2024 · US
Compound arrays for sample profiling
US8969255B2 · US · B2
| Field | Value |
|---|---|
| Publication number | US-8969255-B2 |
| Application number | US-201213683778-A |
| Country | US |
| Kind code | B2 |
| Filing date | Nov 21, 2012 |
| Priority date | Jun 19, 2009 |
| Publication date | Mar 3, 2015 |
| Grant date | Mar 3, 2015 |
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Abstract
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The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds binding to components of the samples can be increased by forming arrays such that multivalent components of the samples (e.g., antibodies or cells) can bind to more than one molecule of a compound at the same time. When a sample is applied to an array under such conditions, the compounds of the array bind to component(s) of the sample with significantly different avidities generating a profile characteristic of the sample.
First claim
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What is claimed is: 1. A method of determining a status of a subject, comprising: (a) contacting a sample from the subject comprising at least 100 different antibodies, wherein not all of the at least 100 different antibodies are autoantibodies, with an array of immobilized different peptides of between 10-30 amino acids in length, wherein each different peptide has a unique amino acid sequence, each of the immobilized different peptides occupying different features of the array,…
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Chemistry & Metallurgy · mapped topic
Physics · mapped topic
Physics · mapped topic
- G01N33/54306Primary
Physics · mapped topic
- G01N33/543Primary
Physics · mapped topic
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- What does patent US8969255B2 cover?
- The invention provides arrays of compound for use in profiling samples. The arrays include compounds bind to components of the samples at relatively low affinities. The avidity of compounds binding to components of the samples can be increased by forming arrays such that multivalent components of the samples (e.g., antibodies or cells) can bind to more than one molecule of a compound at the sam…
- Who is the assignee on this patent?
- Univ Arizona, Univ Arizona
- What technology area does this patent fall under?
- Primary CPC classification G01N33/54306. Mapped technology areas include Physics.
- When was this patent published?
- Publication date Tue Mar 03 2015 00:00:00 GMT+0000 (Coordinated Universal Time) (B2). Legal status and post-grant events are not shown on this page.
- What related patents are in patentsdb?
- We list 8 related publications on this page (citations in our corpus or others sharing the same primary CPC).